Pegylated synthetic human c-peptide

Pegylated synthetic human c-peptide retains bioactivity comparable to that of natural (i.e. non-polyethylene glycolated) C-peptides and has a prolonged circulating residence time in plasma for use in diabetic peripheral neuropathy studies[1].

Product Specifications

CAS Number

[1350661-05-0]

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/pegylated-synthetic-human-c-peptide.html

Solubility

10 mM in DMSO

Smiles

O=C(CCC(C(NC(C)C(NC(CCC(O)=O)C(NC(CC(O)=O)C(NC(CC(C)C)C(NC(CCC(N)=O)C(NC(C(C)C)C(NCC(NC(CCC(N)=O)C(NC(C(C)C)C(NC(CCC(O)=O)C(NC(CC(C)C)C(NCC(NCC(NCC(N1CCCC1C(NCC(NC(C)C(NCC(NC(CO)C(NC(CC(C)C)C(NC(CCC(N)=O)C(N2CCCC2C(NC(CC(C)C)C(NC(C)C(NC(CC(C)C)C(NC(CCC(O)=O)C(NCC(NC(CO)C(NC(CC(C)C)C(NC(CCC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC(CCCC(NCCCOCC(COCCOC)OCCOC)=O)=O)O

Molecular Formula

C129H211N35O48

Molecular Weight

3018.52

References & Citations

[1]Dennis Naas, et al. A 9-Month Toxicity and Toxicokinetic Assessment of Subcutaneous Pegylated Human C-peptide (CBX129801) in Cynomolgus Monkeys. Int J Toxicol. 2015 Jul-Aug;34 (4) :318-24.