DPTN (dihydrochloride)
DPTN is a potent and selective human, mouse, and rat A3AR antagonist with Ki values of 1.65, 9.61, and 8.53 nM, respectively[1].
Product Specifications
CAS Number
[325767-87-1]
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dptn-dihydrochloride.html
Purity
98.47
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=CN=C1)NC2=NC(C3=CC(C)=CC(C)=C3)=C(C4=CC=NC=C4)S2.Cl.Cl
Molecular Formula
C22H20Cl2N4OS
Molecular Weight
459.39
References & Citations
[1]Zhan-Guo Gao, et al. Pharmacological characterization of DPTN and other selective A3 adenosine receptor antagonist. Purinergic Signal. 2021 Dec;17 (4) :737-746.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A3 receptor (A3R)
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
