NNC 92-1687
NNC 92-1687 is a non-peptide competitive human glucagon receptor antagonist (IC50=20 μM; Ki=9.1 μM) . NNC 92-1687 can be used in the research of type 2 diabetes[1].
Product Specifications
CAS Number
22903-37-3
Product Name Alternative
NPC,NPC (hydrochloride)
UNSPSC
12352005
Target
GCGR
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/nnc-92-1687.html
Purity
98.74
Solubility
DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(CSC1=NC2=C(N1)C=CC=C2)C3=CC=C(C(O)=C3)O
Molecular Formula
C15H12N2O3S
Molecular Weight
300.33
References & Citations
[1]Madsen P, et al. Discovery and structure− activity relationship of the first non-peptide competitive human glucagon receptor antagonists[J]. Journal of medicinal chemistry, 1998, 41 (26) : 5150-5157.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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