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2-Nitro-5-thiocyanatobenzoic acid

Product Specifications

UNSPSC Description

2-Nitro-5-thiocyanatobenzoic acid (NTCB) is a highly reactive reagent that transfers its cyano group rapidly to a nucleophilic thiolate. 2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives[1][2].

Target Antigen

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-nitro-5-thiocyanatobenzoic-acid.html

Smiles

O=C(O)C1=CC(SC#N)=CC=C1[N+]([O-])=O

Molecular Weight

224.197

References & Citations

[1]Qiao Y, et al. Site-Specific Conversion of Cysteine in a Protein to Dehydroalanine Using 2-Nitro-5-thiocyanatobenzoic Acid. Molecules. 2021;26(9):2619. Published 2021 Apr 29.|[2]Price NC. Alternative products in the reaction of 2-nitro-5-thiocyanatobenzoic acid with thiol groups. Biochem J. 1976;159(1):177-180.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-137541/2-Nitro-5-thiocyanatobenzoic-acid-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-137541/2-Nitro-5-thiocyanatobenzoic-acid-SDS-MedChemExpress.pdf

CAS Number

30211-77-9

Available Sizes

Curated Selection

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