Azidoacetic Acid
Azidoacetic Acid (2-Azidoacetic acid) (compound 92-1) is a click chemistry reagent containing an azide group. Azidoacetic Acid can be used as a small molecule tool for the synthesis of PROTAC[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
18523-48-3
Product Name Alternative
2-Azidoacetic acid
UNSPSC
12352211
Hazard Statement
H225
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/azidoacetic-acid.html
Purity
99.09
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
[N-]=[N+]=NCC(O)=O
Molecular Formula
C2H3N3O2
Molecular Weight
101.06
Precautions
H225
References & Citations
[1]Ma Xin et al. Class of novel Smad3 protein degraders and application. Patent WO2022148459A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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