(R) -CCG-1423
(R) -CCG-1423 is an inhibitor of RhoA. (R) -CCG-1423 inhibits downstream of Rho and shows specificity for SRE[1].
Product Specifications
CAS Number
[2309931-09-5]
UNSPSC
12352005
Target
Akt; PI3K; Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-ccg-1423.html
Smiles
ClC(C=C1)=CC=C1NC([C@@H](C)ONC(C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=O)=O
Molecular Formula
C18H13ClF6N2O3
Molecular Weight
454.75
References & Citations
[1]Chris R Evelyn, et al. CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling. Mol Cancer Ther. 2007 Aug;6 (8) :2249-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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