Senaparib (hydrochloride)
Product Specifications
UNSPSC Description
Senaparib hydrochloride (IMP4297 hydrochloride) is an oral, selective PARP1/2 inhibitor with potent anti-tumor activity. Senaparib hydrochloride shows antitumor activity against advanced ovarian cancer[1].
Target Antigen
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/senaparib-hydrochloride.html
Smiles
O=C1NC(N(CC2=CC=C(C(C(N3CCN(CC3)C4=NC=CC=N4)=O)=C2)F)C5=C1C(F)=CC=C5)=O.Cl
Molecular Weight
514.91
References & Citations
[1]P. de Souza, et al. 574P Updated results of phase I study of senaparib (IMP4297) in Australian patients with advanced solid tumours. ABSTRACT ONLY| VOLUME 31, SUPPLEMENT 4, S490, SEPTEMBER 01, 2020.|[2]Senaparib as first-line maintenance therapy in advanced ovarian cancer: a randomized phase 3 trial
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-137450A/Senaparib-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-137450A/
Clinical Information
Phase 2
CAS Number
1401683-39-3
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