DOTA-tris (tBu) ester NHS ester

DOTA-tris (tBu) ester NHS ester is a bifunctional precursor to a DOTA-based chelating agent. DOTA-tris (tBu) ester NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules, and upon deprotection forms stable complexes with metal ions for applications in molecular imaging[1].

Product Specifications

CAS Number

[819869-77-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dota-tris-tbu-ester-nhs-ester.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(ON1C(CCC1=O)=O)CN2CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CC2

Molecular Formula

C32H55N5O10

Molecular Weight

669.81

Precautions

H302, H315, H319, H335

References & Citations

[1]Wängler C, et, al. Improved syntheses and applicability of different DOTA building blocks for multiply derivatized scaffolds. Bioorg Med Chem. 2008 Mar 1; 16 (5) : 2606-16.