Kukoamine B (mesylate)
Kukoamine B, a spermine alkaloid, is a potent dual LPS and CpG DNA inhibitor with Kd values of 1.23 µM and 0.66 µM, respectively. Kukoamine B exerts anti-inflammatory, anti-diabetic, anti-oxidant, anti-osteoporotic and neuroprotective effects. Kukoamine B has the potential for the study of sepsis. [1][2][3][4].
Product Specifications
CAS Number
[1375179-86-4]
UNSPSC
12352005
Target
Akt; Apoptosis; DNA/RNA Synthesis; MARK; MMP; PI3K; ROS Kinase
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kukoamine-b-mesylate.html
Smiles
O=C(CCC1=CC=C(C(O)=C1)O)NCCCNCCCCN(CCCN)C(CCC2=CC=C(C(O)=C2)O)=O.O=S(O)(C)=O
Molecular Formula
C29H46N4O9S
Molecular Weight
626.76
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items