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Zampilimab

Product Specifications

UNSPSC Description

Zampilimab (UCB-7858) is a monoclonal antibody against transglutaminase 2 (TG2). Zampilimab has potential application in renal transplant[1][2].

Target Antigen

Glutaminase

Type

Inhibitory Antibodies

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/zampilimab.html

Purity

98.81

Solubility

10 mM in DMSO

Smiles

[Zampilimab]

References & Citations

[1]Tempest R, et al. The Biological and Biomechanical Role of Transglutaminase-2 in the Tumour Microenvironment. Cancers (Basel). 2021 Jun 3;13(11):2788.|[2]Prat-Duran J, et al. Transglutaminase 2 as a novel target in chronic kidney disease - Methods, mechanisms and pharmacological inhibition. Pharmacol Ther. 2021 Jun;222:107787.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P99512/Zampilimab-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P99512/Zampilimab-SDS-MedChemExpress.pdf

Clinical Information

Phase 2

CAS Number

2098280-42-1

Available Sizes

Curated Selection

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