WRN inhibitor 1
WRN inhibitor 1 is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor that inhibits WRN helicase domain activity. WRN inhibitor 1 can be used in the study of cancer[1].
Product Specifications
CAS Number
[2923008-44-8]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wrn-inhibitor-1.html
Purity
98.05
Solubility
DMSO : ≥ 130 mg/mL
Smiles
O=C1NC(C2=CC=C(F)C=C2)=CC=C1C(NC3C=CS(=O)(C3)=O)=O
Molecular Formula
C16H13FN2O4S
Molecular Weight
348.35
References & Citations
[1]Ashely, et al. Cyclic vinyl sulfone compounds as wrn inhibitors. WO2023062575A1. 2023-04-20.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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