ACTH (11-24) (acetate)

ACTH (11-24) (acetate) is an adrenocorticotropic hormone (ACTH) receptor antagonist. ACTH (11-24) is a fragment of adrenocorticotropic and induces cortisol release. ACTH (11-24) can be used for the research of central nervous system[1].

Product Specifications

Product Name Alternative

Adrenocorticotropic Hormone (11-24) (acetate)

UNSPSC

12352209

Target

Melanocortin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/acth-11-24-acetate.html

Purity

99.88

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC3=CC=C(C=C3)O)C(N4[C@@H](CCC4)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N.CC(O)=O.[x]

Molecular Formula

C77H134N24O16·xC2H4O2

Molecular Weight

1652.04 (free base)

References & Citations

[1]Li ZG, et al. Adrenocorticotropin (1-10) and - (11-24) promote adrenal steroidogenesis by different mechanisms. Endocrinology. 1989 Aug;125 (2) :592-6.|[2]P F Brain, et al. Acute influences of some ACTH-related peptides of fighting and adrenocortical activity in male laboratory mice. Pharmacol Biochem Behav