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HIV-1 inhibitor-72

HIV-1 inhibitor-72 (compound 5m) is a target protein ligand of PROTAC Vif degrader-1 (HY-163851) . HIV-1 inhibitor-72 is a potent HIV-1 inhibitor[1].

Product Specifications

CAS Number

[2801703-79-5]

UNSPSC

12352005

Target

HIV; Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

Anti-infection; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/hiv-1-inhibitor-72.html

Smiles

COC1=CC=C(C=C1NC(C2=C(C=CC=C2SC3=CC=C(C=C3)[N+]([O-])=O)N)=O)O

Molecular Formula

C20H17N3O5S

Molecular Weight

411.43

References & Citations

[1]Luo D, et al. Discovery of L15 as a novel Vif PROTAC degrader with antiviral activity against HIV-1. Bioorg Med Chem Lett. 2024 Jul 10;111:129880.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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