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Garvicin KS, GakB

Garvicin KS, GakB is a peptide at sizes of 34 amino acids to form bacteriocin garvicin KS (GarKS), with other 2 peptides, GakA, and GakC. Garvicin KS, GakB inhibits fibroblast viability and proliferation. Garvicin KS, GakB with GakA, is a potent combination with good peptide stability, antimicrobial efficacy, and fibroblast viability/proliferation effects. Garvicin KS peptides inhibit MSSA with MIC values in the order GakB >GakC >GakA[1].

Product Specifications

CAS Number

2098351-25-6

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/garvicin-ks-gakb.html

Solubility

10 mM in DMSO

Smiles

[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CCSC)N)=O)=O)C)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCCN)=O)C)=O)=O)C)=O)CCCCN)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)=O)CCCCN)=O)=O)CC(C)C)=O)CC(C)C)=O)=O)=O)C)=O)C)=O)=O)=O)C)=O)[C@@H](C)O)=O)C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(NCC(O)=O)=O)=O)[C@H](CC)C)=O)CCCCN)=O)CCCCN)=O)CC(C)C)=O)=O)=O

Molecular Formula

C145H247N39O37S

Molecular Weight

3160.82

References & Citations

[1]Thapa RK, et al. Preformulation studies on novel garvicin KS peptides for topical applications. Eur J Pharm Sci. 2020 Aug 1;151:105333.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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