6-Acetylnimbandiol
6-Acetylnimbandiol (6-O-Acetylnimbandiol) is a non-cytotoxic tyrosinase inhibitor (IC50=69.85 μM) that effectively inhibits melanin production and MITF expression. 6-Acetylnimbandiol can be used in melanoma research[1].
Product Specifications
CAS Number
[1281766-66-2]
Product Name Alternative
6-O-Acetylnimbandiol
UNSPSC
12352005
Target
Tyrosinase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-acetylnimbandiol.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@@H]([C@@]3([C@@]([C@](O)(C=CC3=O)C)([H])[C@H]([C@@]1([H])O[C@@]4([H])C2=C([C@@](C5=COC=C5)([H])C4)C)OC(C)=O)C)CC(OC)=O
Molecular Formula
C28H34O8
Molecular Weight
498.56
References & Citations
[1]Su S, et al. Melanogenesis-inhibitory activities of limonoids and tricyclic diterpenoids from Azadirachta indica. Bioorg Chem. 2020 Jul;100:103941.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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