6-Acetylnimbandiol

6-Acetylnimbandiol (6-O-Acetylnimbandiol) is a non-cytotoxic tyrosinase inhibitor (IC50=69.85 μM) that effectively inhibits melanin production and MITF expression. 6-Acetylnimbandiol can be used in melanoma research[1].

Product Specifications

CAS Number

[1281766-66-2]

Product Name Alternative

6-O-Acetylnimbandiol

UNSPSC

12352005

Target

Tyrosinase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/6-acetylnimbandiol.html

Solubility

10 mM in DMSO

Smiles

C[C@]12[C@@H]([C@@]3([C@@]([C@](O)(C=CC3=O)C)([H])[C@H]([C@@]1([H])O[C@@]4([H])C2=C([C@@](C5=COC=C5)([H])C4)C)OC(C)=O)C)CC(OC)=O

Molecular Formula

C28H34O8

Molecular Weight

498.56

References & Citations

[1]Su S, et al. Melanogenesis-inhibitory activities of limonoids and tricyclic diterpenoids from Azadirachta indica. Bioorg Chem. 2020 Jul;100:103941.