6-Chloroguanineriboside
6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analog. 6-Chloroguanineriboside has extremely low affinity for guanosine binding sites in rat brain (Ki: 253.1 μM) [1][2].
Product Specifications
CAS Number
2004-07-1
Product Name Alternative
6-Chloroguanosine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/6-chloroguanineriboside.html
Concentration
10mM
Purity
98.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)N=C3Cl)=C3N=C2)O[C@@H]1CO
Molecular Formula
C10H12ClN5O4
Molecular Weight
301.69
Precautions
H302, H315, H319, H335
References & Citations
[1]Traversa U, et al. Rat brain guanosine binding site. Biological studies and pseudo-receptor construction. Bioorg Med Chem. 2003 Dec 1;11 (24) :5417-25.|[2]Kikugawa K, et al. Platelet aggregation inhibitors. 2. Inhibition of platelet aggregation by 5'-, 2-, 6-, and 8-substituted adenosines. J Med Chem. 1972 Apr;15 (4) :387-90.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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