6-Chloroguanineriboside

6-Chloroguanineriboside (6-Chloroguanosine) is a purine nucleoside analog. 6-Chloroguanineriboside has extremely low affinity for guanosine binding sites in rat brain (Ki: 253.1 μM) [1][2].

Product Specifications

CAS Number

[2004-07-1]

Product Name Alternative

6-Chloroguanosine

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/6-chloroguanineriboside.html

Concentration

10mM

Purity

98.46

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)N=C3Cl)=C3N=C2)O[C@@H]1CO

Molecular Formula

C10H12ClN5O4

Molecular Weight

301.69

Precautions

H302, H315, H319, H335

References & Citations

[1]Traversa U, et al. Rat brain guanosine binding site. Biological studies and pseudo-receptor construction. Bioorg Med Chem. 2003 Dec 1;11 (24) :5417-25.|[2]Kikugawa K, et al. Platelet aggregation inhibitors. 2. Inhibition of platelet aggregation by 5'-, 2-, 6-, and 8-substituted adenosines. J Med Chem. 1972 Apr;15 (4) :387-90.