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CTLA-4, Human (HEK293, GST)

CTLA-4 Protein, Human (HEK293, GST) is negative regulator of T-cell immune function.

Product Specifications

Product Name Alternative

CTLA-4 Protein, Human (HEK293, GST), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/ctla-4-protein-human-hek293-gst.html

Purity

96.77

Smiles

KAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSD

Molecular Formula

1493 (Gene_ID) P16410 (K36-D161) (Accession)

Molecular Weight

40-55 kDa

References & Citations

[1]Harper K, et, al. CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location. J Immunol. 1991 Aug 1;147 (3) :1037-44.|[2]Buchbinder EI, et, al. CTLA-4 and PD-1 Pathways: Similarities, Differences, and Implications of Their Inhibition. Am J Clin Oncol. 2016 Feb;39 (1) :98-106.|[3]Rowshanravan B, et, al. CTLA-4: a moving target in immunotherapy. Blood. 2018 Jan 4;131 (1) :58-67.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

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