β-Yohimbine

β-Yohimbine (Amsonin) is an indole alkaloid that can be isolated from Aspidosperma ulei Markgr. β-Yohimbine shows antiplasmodial activity against the Chloroquine (HY-17589A) -resistant Fc M29-Cameroon strain (IC50: > 1 μg/mL) [1].

Product Specifications

CAS Number

[549-84-8]

Product Name Alternative

Amsonin; Amsonine; NSC 93133

UNSPSC

12352005

Target

Parasite

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/β-yohimbine.html

Solubility

10 mM in DMSO

Smiles

COC([C@@H]1[C@@]2([H])C[C@@]3([H])C4=C(CCN3C[C@]2([H])CC[C@H]1O)C5=C(C=CC=C5)N4)=O

Molecular Formula

C21H26N2O3

Molecular Weight

354.44

References & Citations

[1]dos Santos Torres ZE, et al. Chemical composition of Aspidosperma ulei Markgr. and antiplasmodial activity of selected indole alkaloids. Molecules. 2013 May 29;18 (6) :6281-97.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N2932/β-Yohimbine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N2932/

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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