β-Yohimbine
β-Yohimbine (Amsonin) is an indole alkaloid that can be isolated from Aspidosperma ulei Markgr. β-Yohimbine shows antiplasmodial activity against the Chloroquine (HY-17589A) -resistant Fc M29-Cameroon strain (IC50: > 1 μg/mL) [1].
Product Specifications
CAS Number
[549-84-8]
Product Name Alternative
Amsonin; Amsonine; NSC 93133
UNSPSC
12352005
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/β-yohimbine.html
Solubility
10 mM in DMSO
Smiles
COC([C@@H]1[C@@]2([H])C[C@@]3([H])C4=C(CCN3C[C@]2([H])CC[C@H]1O)C5=C(C=CC=C5)N4)=O
Molecular Formula
C21H26N2O3
Molecular Weight
354.44
References & Citations
[1]dos Santos Torres ZE, et al. Chemical composition of Aspidosperma ulei Markgr. and antiplasmodial activity of selected indole alkaloids. Molecules. 2013 May 29;18 (6) :6281-97.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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