LB-60-OF61

LB-60-OF61 is a NAMPT inhibitor and is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines[1].

Product Specifications

CAS Number

[794461-93-1]

UNSPSC

12352005

Target

NAMPT

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/lb-60-of61.html

Concentration

10mM

Purity

99.25

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(OCC2=CC3=C(N=C(C#N)N=C3)N2CCC4CCCCC4)C=C1)NCC5=CC=CN=C5

Molecular Formula

C29H30N6O2

Molecular Weight

494.59

References & Citations

[1]Estoppey D, et al. Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells. Sci Rep. 2017 Feb 16;7:42728.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MR206434 10 µg

Slc22a18 (NM_001042760) Mouse Tagged ORF Clone

Ask

View Details

PVT43697 2 µg

pCMV-SPORT6-Mettl3 Plasmid

Ask

View Details

135335-Biotin 100 µL

WBSCR22 (Williams-Beuren Syndrome Chromosomal Region 22 Protein, Uncharacterized Methyltransferase WBSCR22, HUSSY-03, PP3381, HASJ4442, MERM1, WBMT) (Biotin)

Ask

View Details

NB100-423DL594 0.1 mL

Rabbit Polyclonal FKBP15 Antibody [DyLight 594]

Ask

View Details

EK730858 96 Well

Mouse Fibroblast growth factor receptor 2 (FGFR2) Elisa Kit

Ask

View Details