LB-60-OF61
LB-60-OF61 is a NAMPT inhibitor and is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines[1].
Product Specifications
CAS Number
[794461-93-1]
UNSPSC
12352005
Target
NAMPT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lb-60-of61.html
Concentration
10mM
Purity
99.25
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(OCC2=CC3=C(N=C(C#N)N=C3)N2CCC4CCCCC4)C=C1)NCC5=CC=CN=C5
Molecular Formula
C29H30N6O2
Molecular Weight
494.59
References & Citations
[1]Estoppey D, et al. Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells. Sci Rep. 2017 Feb 16;7:42728.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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