3-Hydroxykynurenine
3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis[1].
Product Specifications
CAS Number
484-78-6
Product Name Alternative
3-Hydroxy-DL-kynurenine
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Apoptosis; Endogenous Metabolite
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/3-hydroxykynurenine.html
Purity
99.90
Solubility
1M HCl : 33.33 mg/mL (ultrasonic; adjust pH to 1 with HCl) |DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C(N)CC(C1=CC=CC(O)=C1N)=O
Molecular Formula
C10H12N2O4
Molecular Weight
224.21
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Frequently Asked Questions
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