Human Raf-1 Protein Kinase

<strong>Human Raf-1 Protein Kinase</strong>_x000D_ <strong>Catalog number:</strong> B2013329_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 74 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Raf-1 Protein Kinase human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Odabaei G, Chatterjee D, Jazirehi AR, Goodglick L, Yeung K, Bonavida B. Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis Adv Cancer Res. 2004;91:169-200._x000D_ 2: Mas VM, Hernandez H, Plo I, Bezombes C, Maestre N, Quillet-Mary A, Filomenko R, Demur C, Jaffrézou JP, Laurent G. Protein kinase Czeta mediated Raf-1/extracellular-regulated kinase activation by daunorubicin Blood. 2003 Feb 15;101(4):1543-50._x000D_ 3: Hindley A, Kolch W. Raf-1 and B-Raf promote protein kinase C theta interaction with BAD Cell Signal. 2007 Mar;19(3):547-55._x000D_ 4: Magnuson NS, Beck T, Vahidi H, Hahn H, Smola U, Rapp UR. The Raf-1 serine/threonine protein kinase Semin Cancer Biol. 1994 Aug;5(4):247-53._x000D_ 5: King AJ, Sun H, Diaz B, Barnard D, Miao W, Bagrodia S, Marshall MS. The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338 Nature. 1998 Nov 12;396(6707):180-3._x000D_ 6: Illario M, Cavallo AL, Bayer KU, Di Matola T, Fenzi G, Rossi G, Vitale M. Calcium/calmodulin-dependent protein kinase II binds to Raf-1 and modulates integrin-stimulated ERK activation J Biol Chem. 2003 Nov 14;278(46):45101-8._x000D_ 7: Hambleton J, McMahon M, DeFranco AL. Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events J Exp Med. 1995 Jul 1;182(1):147-54._x000D_ 8: Kharbanda S, Saleem A, Emoto Y, Stone R, Rapp U, Kufe D. Activation of Raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells J Biol Chem. 1994 Jan 14;269(2):872-8._x000D_ 9: Lee M, Koh WS, Han SS. Down-regulation of Raf-1 kinase is associated with paclitaxel resistance in human breast cancer MCF-7/Adr cells Cancer Lett. 2003 Apr 10;193(1):57-64._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/9722588">10: Hood J, Granger HJ. Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells J Biol Chem. 1998 Sep 4;273(36):23504-8. </a>_x000D_ _x000D_ <strong>Products Related to Human Raf-1 Protein Kinase can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>