PVP-037
PVP-037 is a potent TLR7 and TLR8 agonist adjuvant. PVP-037 shows broad innate immune activation and enhances vaccine immune responses [1].
Product Specifications
CAS Number
[862810-50-2]
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pvp-037.html
Smiles
CCC(C1=CC=CC=C1)C(NC2=C(C)C=CC(C3=CN4C=CC=NC4=N3)=C2)=O
Molecular Formula
C23H22N4O
Molecular Weight
370.45
References & Citations
[1]Soni D, et al. From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation. Sci Adv. 2024 Jul 5;10 (27) :eadg3747.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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