LUF6000
LUF6000 is an orally active allosteric modulator of the A3 adenosine receptor. LUF6000 has potent anti-inflammatory effect[1][2].
Product Specifications
CAS Number
890087-21-5
UNSPSC
12352005
Hazard Statement
H302
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/LUF6000.html
Purity
99.09
Solubility
DMSO : 14.29 mg/mL (ultrasonic)
Smiles
ClC1=CC(NC2=NC3=C(C=CC=C3)C4=C2NC(C5CCCCC5)=N4)=CC=C1Cl
Molecular Formula
C22H20Cl2N4
Molecular Weight
411.33
Precautions
P264-P270-P330-P501
References & Citations
[1]Du L, et al. Species differences and mechanism of action of A3 adenosine receptor allosteric modulators. Purinergic Signal. 2018;14 (1) :59-71.|[2]Cohen S, et al. A₃ adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action. Mediators Inflamm. 2014;2014:708746.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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