Pinocembrin

Pinocembrin ((+) -Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties[1].

Product Specifications

CAS Number

[480-39-7]

Product Name Alternative

(+) -Pinocoembrin; Dihydrochrysin; Galangin flavanone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; Bacterial; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Anti-infection; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/Pinocembrin.html

Concentration

10mM

Purity

99.67

Solubility

DMSO : 83.33 mg/mL (ultrasonic)

Smiles

O=C1C[C@@H](C2=CC=CC=C2)OC3=CC(O)=CC(O)=C13

Molecular Formula

C15H12O4

Molecular Weight

256.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Hanieh H, et al. Pinocembrin, a novel histidine decarboxylase inhibitor with anti-allergic potential in in vitro. Eur J Pharmacol. 2017 Nov 5;814:178-186.