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MICROVUETMPTH ELISA (High Sensitive)

The MICROVUE High Sensitivity Human PTH (1-34) ELISA Kit is for the measurement of Human PTH (1-34) in plasma or cell culture media.

Product Specifications

Background

Over the years, studies involving the intermittent dosing of human PTH (1-34) in animals and humans have demonstrated an anabolic effect on bone. This effect was positive for bone mass, size, structure, and strength, demonstrating the antifracture efficacy of the treatment. The FDA has approved the recombinant form of human PTH (1-34) – rhPTH (1-34) or teriparatide, for treatment of many forms of osteoporosis. The measurement of circulating levels of this peptide/drug may be useful in assessing its pharmacological properties and for appropriate dosing and schedule optimization. Additionally, this assay may be useful in screening samples for both endogenous levels of circulating hPTH (1-34) and elevated levels of this peptide as it may interfere to varying degrees with 2-site immunometric assays used for measuring intact PTH (1-84) .

Cross Reactivity

Rat

Assay Performance Time

3.5 hours

Standard

7

Sample Type

Plasma or Cell Culture Supernatent, 300 μL

Limit Of Detection

0.9 pg/mL

Form

96 well plate with 12 eight-well strips in a resealable foil pouch

Storage Conditions

Store unopened kit between 2°C to 8°C. Refer to manual for storing individual components

Controls

2

Inter Assay

6.2 - 8.5%

Intra Assay

2.1 - 2.6%

Frequently Asked Questions

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