MICROVUETMCIC-C1q Controls

The CIC-C1q Controls are intended for use as controls in the MICROVUE CIC EIA and contains one vial each of Low (Normal) and High (Abnormal) Control with volumes sufficient for single use.

Product Specifications

Background

Elevated circulating immune complexes (CIC) have been detected in serum or plasma obtained from patients with a variety of diseases, for example, from patients with autoimmune disorders, leukemia, various cancers, bacterial or viral infections. CIC determinations can be important in the diagnosis or prognosis of certain diseases (e.g., SLE1 and rheumatoid arthritis) . Several immunological techniques such as the Raji Cell assay, C1q deviation test, conglutinin test, fluid phase C1q binding procedures, rheumatoid factor assay, PEG precipitin test, and solidphase C1q assays have been described to detect or quantitate CIC. The MICROVUETM CIC EIA uses human C1q in the solid phase to capture CIC.