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Factor P Depleted Sera

Normal human serum depleted of complement Factor P protein.

Product Specifications

Background

Normal human serum was depleted of factor P (properdin) by immunoaffinity chromatography. The product is tested for the absence of factor P by double immunodiffusion. Factor P is a positive regulator of alternative pathway complement activation. As a result, Factor P-Dpl is still capable of activating the alternative pathway but activation is slower than with properdin present.

Source

Normal human serum

Applications

See citations and technical data sheet for application info.

Concentration

>50 mg protein/mL (refer to CoA for lot specific concentration) .

Purity

No Factor P detectable by immunodiffusion.

Activity

>80% versus normal human serum standard.

Form

Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 μm filtered.

Storage Conditions

Store at -70°C or below. Minimize freeze/thaw cycles.

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