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Factor D Protein

Purified human Factor D protein

Product Specifications

Background

Purified human complement Factor D. Factor D is unique to the Alternative Complement Pathway. It consists of a single peptide chain with a molecular weight of 24 kD. Factor D is a specific serine protease which cleaves Factor B complexed with C3b (or hydrolyzed C3) in a single position to yield Bb and Ba.

Source

Normal human serum

Applications

See citations and technical data sheet for application info.

Concentration

0.1 mg/mL (refer to CoA for lot specific concentration)

Purity

>90% by SDS-PAGE

Activity

>95% versus normal human serum standard

Form

Frozen liquid. 10 mM Sodium phosphate, 145 mM NaCl, pH 7.2. No preservative, 0.22 μm filtered.

Molecular Weight

24,000 Da (single chain)

Storage Conditions

Store at -70°C or below. Avoid freeze/thaw.

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