What is the catalog number for C7 Antibody (Monoclonal)?

The catalog number for C7 Antibody (Monoclonal) is A221.

What sizes are available for C7 Antibody (Monoclonal)?

C7 Antibody (Monoclonal) is available in the following size(s): 100 µL.

Is C7 Antibody (Monoclonal) in stock?

C7 Antibody (Monoclonal) is currently made to order / not held in immediate stock. Contact us for lead time.

C7 Antibody (Monoclonal)

A murine monoclonal antibody to an epitope on C7 protein.

Product Specifications

Background

Complement component C7 is a single-chain glycoprotein with a molecular weight of 95 kD. C7 protein is present in human plasma at an approximate concentration of 55 μg/ml. Upon activation of the lectin, classical or alternative pathways, C7 becomes integrated into the terminal complement complex. The Terminal Complement Complex (TCC) is a general term for both membrane-bound C5b-9, or Membrane Attack Complex (MAC), and fluid phase SC5b-9. TCC is an excellent marker for quantifying the extent of terminal pathway activation in vivo or in vitro. TCC can be deposited on the surface of transformed cells, biomaterials, as well as, a variety of other materials.

Cross Reactivity

Human, Bovine, Cat, Dog, Hamster, Horse, Rabbit, Rat.

Immunogen

Purified human protein.

Clonality

Monoclonal

Source

Mouse

Applications

See citations and technical data sheet for application info.

Concentration

1.0-1.2 mg/mL

Purity

≥ 95% by SDS PAGE

Form

Liquid. Borate Buffered Saline (pH 8.4 ± 0.2), with ≤ 0.1% Sodium Azide.

Storage Conditions

Short term (30 days) 4 ̊C. Long term at or below –20 ̊C.

Specificity

This monoclonal antibody was raised against purified human C7. It is specific for an Antigen expressed on native C7 but not expressed in MAC. It will inhibit the lysis of EA and will not detect membrane bound MAC.