C3d Protein
Purified human C3d protein
Product Specifications
Background
C3d is derived from human C3 after a series of proteolytic cleavages. Trypsin-like enzymes (such as plasmin, thrombin, elastase, etc.) cleave iC3b separating C3c from C3dg (38,900 Da) and C3dg is further digested releasing C3g (5,100 Da) to leave C3d. iC3b (inactivated C3b) is derived from C3b. C3b itself is produced by all three pathways of complement when native C3 is cleaved releasing C3a.
Source
Normal human serum
Applications
See citations and technical data sheet for application info.
Concentration
1.0 mg/mL (refer to CoA for lot specific concentration)
Purity
>85% by SDS-PAGE
Activity
No activity
Form
Frozen liquid. 10 mM Sodium phosphate, 145 mM NaCl, pH 7.2. No preservative, 0.22 μm filtered.
Molecular Weight
33,800 Da (single chain)
Storage Conditions
Store at -70°C or below. Avoid freeze/thaw.
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