C3 Protein
Purified human C3 protein
Product Specifications
Background
Purified human complement component C3. The third component of complement is a centrally important constituent of both the alternative and classical pathways. Upon secretion, pro-C3 undergoes a site specific proteolytic cleavage to yield circulating C3, a protein containing two disulfide bonded subunits (Alpha 115 kD and Beta 75 kD) . The concentration of C3 in serum is approximately 1.25 +/– 0.52 mg/mL.
Source
Normal human serum
Applications
See citations and technical data sheet for application info.
Concentration
1.0 mg/mL (refer to CoA for lot specific concentration)
Purity
>85% by SDS-PAGE
Activity
>70% versus normal human serum standard
Form
Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.2. No preservative, 0.22 μm filtered.
Molecular Weight
185,000 Da (2 chains)
Storage Conditions
Store at -70°C or below. Avoid freeze/thaw (>10 % activity loss per thaw) .
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