MICROVUETMDPD EIA
The MICROVUE DPD EIA offers a laboratory test that measures deoxypyridinoline cross-links (Dpd) .
Product Specifications
Background
DPD is a specific marker of bone resorption which is excreted in the urine. MicroVue DPD EIA provides a quantitative measure of deoxypyridinoline (Dpd), a cross-link of bone type 1 collagen released during the resorption process. Dpd is excreted unmetabolized in urine. Elevated levels of urinary Dpd indicate elevated bone resorption in individuals. MicroVue DPD is a urinary assay that provides a quantitative measure of the excretion of deoxypyridinoline (DPD) crosslinks as an indicator of bone resorption. Elevated levels of urinary DPD indicate elevated bone resorption in individuals. Measurement of DPD is intended for use as an aid in monitoring bone resorption changes in postmenopausal women receiving hormonal or bisphosphonate antiresorptive therapies and in individuals diagnosed with osteoporosis.
Cross Reactivity
Baboon, Cow, Cynomolgous monkey, Dog, Guinea pig, Horse, Mouse, Pig, Rabbit, Rat, Rhesus monkey, Sheep, Squirrel monkey
Assay Performance Time
3 hours
Standard
6
Sample Type
Urine 50 μL
Sample Volume
Females (Ages 25–44) 3.0–7.4 nmol DPD/nmol Creatinine, Males (Ages 25–55) 2.3–5.4 nmol DPD/nmol Creatinine
Limit Of Detection
1.1 nmol/L
Form
96 well plate with 12 eight-well strips in a resealable foil pouch
Storage Conditions
Store unopened kit between 2°C to 8°C. Refer to manual for storing individual components
Limit Of Quantification
300 nmol/L
Controls
2
Inter Assay
3.1–4.8%
Intra Assay
4.3–8.4%
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