MICROVUETMCICP EIA
The MICROVUE CICP assay measures type I C-terminal collagen propeptide (CICP) in serum.
Product Specifications
Background
Collagen, the triple-helical molecule which forms the fibrous framework of all connective tissues, is synthesized as procollagen, a larger precursor molecule. Procollagen consists of mature collagen with extension peptides at both the amino and carboxy termini. These extension peptides, or propeptides, are cleaved from the collagen molecule by specific proteases prior to incorporation of collagen into a growing collagen fibril. The release of these peptides into the circulation provides a stoichiometric representation of the production of collagen.
Cross Reactivity
Cynomolgous monkey, Rabbit, Rhesus monkey
Assay Performance Time
4 hours
Standard
6
Sample Type
Serum 25 μL
Sample Volume
Adult: 69–103 ng/mL, Children: 110–966 ng/mL
Limit Of Detection
0.2 ng/mL
Form
96 well plate with 12 eight-well strips in a resealable foil pouch
Storage Conditions
Store unopened kit between 2°C to 8°C. Refer to manual for storing individual components
Limit Of Quantification
80 ng/mL
Controls
2
Inter Assay
5–7%
Intra Assay
5.5–6.8%
Frequently Asked Questions
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