Tos-PEG2-NH-Boc

Tos-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[192132-77-7]

UNSPSC

12352005

Hazard Statement

H301, H311, H331, H341

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tos-peg2-nh-boc.html

Purity

99.87

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(OC(C)(C)C)NCCOCCOS(=O)(C1=CC=C(C)C=C1)=O

Molecular Formula

C16H25NO6S

Molecular Weight

359.44

Precautions

H301, H311, H331, H341

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; PEG Linkers

Available Sizes

Curated Selection

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