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N1, N3, N5-Tris (4-dodecylhexadecyl) benzene-1,3,5-tricarboxamide

N1, N3, N5-Tris (4-dodecylhexadecyl) benzene-1,3,5-tricarboxamide is an analogue of TT3. TT3 is an ionizable lipid-like materials for mRNA delivery[1][2].

Product Specifications

CAS Number

2922283-38-1

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Liposome

Type

Oligonucleotides

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n1-n3-n5-tris-4-dodecylhexadecyl-benzene-1-3-5-tricarboxamide.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NCCCC(CCCCCCCCCCCC)CCCCCCCCCCCC)C1=CC(C(NCCCC(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)=CC(C(NCCCC(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)=C1

Molecular Formula

C93H177N3O3

Molecular Weight

1385.42

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Li B, Luo X, Deng B, et al. An Orthogonal Array Optimization of Lipid-like Nanoparticles for mRNA Delivery in Vivo. Nano Lett. 2015;15(12):8099-8107. |[2]Jiang C, Mei M, Li B, et al. A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo. Cell Res. 2017;27(3):440-443.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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