Golidocitinib (AZD4205)
Product Specifications
CAS Number
2091134-68-6
Target
JAK
Applications
Angiogenesis
Additionnal Information
Golidocitinib (AZD4205) (Compound 21) is a highly selective and potent inhibitor of Janus kinase 1 (JAK1), with an IC50 of 0.07 μM for JAK1 and much weaker inhibition of JAK2 (IC50 > 15 μM) . It also exhibits potent antitumor effects in NSCLC xenograft models in preclinical studies.
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