NIC3
Product Specifications
CAS Number
494830-67-0
Smiles
CC (C) (C) C1=CC=C (OCC (NCCNC (COC2=CC=C (C (C) (C) C) C=C2) =O) =O) C=C1
Molecular Formula
C26H36N2O4
Additionnal Information
NIC3 is a selective inhibitor of nucleus accumbens-associated protein 1 (NAC1), a BTB/POZ domain-containing transcription corepressor overexpressed in cancers. It binds the conserved Leu-90 residue in NAC1's BTB domain, disrupting homodimerization essential for nuclear body formation and stability.
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