Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

BMS-986260

Product Specifications

CAS Number

2001559-19-7

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Molecular Formula

C18H12ClFN6O

Additionnal Information

BMS-986260 is an orally active immuno-oncology agent that inhibits TGFβR1 with an IC50 of 1.6 nM. It shows selectivity for TGFβR1 compared to TGFβR2 and over 200 other kinases. In MINK and NHLF cell lines, BMS-986260 blocks TGFβ-induced pSMAD2/3 nuclear translocation with IC50 values of 350 nM and 190 nM, respectively.

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Recombinant Xenopus laevis Cytochrome b561 (cyb561)
orb2911766-01 20 µg

Recombinant Xenopus laevis Cytochrome b561 (cyb561)

Sign In for Pricing
View Details
Recombinant Xenopus laevis Cytochrome b561 (cyb561)
orb2911766-02 100 µg

Recombinant Xenopus laevis Cytochrome b561 (cyb561)

Sign In for Pricing
View Details
ZNF563 Antibody (N-term) Blocking Peptide
MBS9222918-01 0.5 mg

ZNF563 Antibody (N-term) Blocking Peptide

Sign In for Pricing
View Details
ZNF563 Antibody (N-term) Blocking Peptide
MBS9222918-02 5x 0.5 mg

ZNF563 Antibody (N-term) Blocking Peptide

Sign In for Pricing
View Details
1-tert-Butyl-3- (2-chloroacetyl) urea
EAA79127-01 250 mg

1-tert-Butyl-3- (2-chloroacetyl) urea

Sign In for Pricing
View Details
1-tert-Butyl-3- (2-chloroacetyl) urea
EAA79127-02 2.5 g

1-tert-Butyl-3- (2-chloroacetyl) urea

Sign In for Pricing
View Details