SS-3091
Product Specifications
CAS Number
2756257-56-2
Target
Ras
Applications
Apoptosis
Smiles
O=C (C1=CC=CC (C (F) (F) F) =C1) NC2=CC=C (C) C (C3=CC4=C (C (C) =C3) N=C (NC5=CC=C6C (C (CN (CC6) C) C) =C5) N=C4) =C2
Molecular Formula
C36H34F3N5O
Additionnal Information
SS-3091 is a pan-KRas inhibitor that targets the interaction interfaces of KRas. By destabilizing the ARaf/KRas complex, it modulates downstream signaling pathways. This compound exhibits activity against KRas G12D, G12C, G12V, and G12S mutants in multiple cancer cell lines.
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