Auceliciclib (AU3-14, Ulecaciclib)
Product Specifications
CAS Number
2075750-05-7
Target
CDK4/6
Applications
Cell Cycle
Smiles
FC1=C (C2=C (C) N=C (NC3CCCC3) S2) N=C (NC4=NC=C (CN5CCN (CC5) CC) C=C4) N=C1
Molecular Formula
C25H33FN8S
Additionnal Information
Ulecaciclib is an orally active cyclin-dependent kinase (CDK) inhibitor with Ki values of 0.62 μM for CDK2/Cyclin A, 0.2 nM for CDK4/Cyclin D1, 3 nM for CDK6/Cyclin D3, and 0.63 μM for CDK7/Cyclin H. This compound demonstrates blood-brain barrier penetration and favorable pharmacokinetic properties.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TA422879 100 µL
Myelin Basic Protein (MBP) Rabbit Monoclonal Antibody
Sign In for Pricing
View Details 
