DY268
Product Specifications
CAS Number
1609564-75-1
Smiles
O=C (C1=CN (CC2=CC (OC) =CC=C2) N=C1C3=CC=C (C) C=C3) NC4=CC=C (C) C (S (=O) (N5CCOCC5) =O) =C4
Molecular Formula
C30H32N4O5S
Additionnal Information
DY268 is a farnesoid X receptor (FXR) antagonist with an IC50 of 7.5 nM. In cellular assays, it inhibits FXR transactivation with an IC50 of 468 nM. This compound has applications in drug-induced liver injury (DILI) research.
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