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PKN1

Product Specifications

CAS Number

942425-34-5

Target

PKC

Applications

Cytoskeletal Signaling

Smiles

CCN1C (C2=CC=NC=C2) =CC3=C1CCNC3=O

Molecular Formula

C14H15N3O

Additionnal Information

PKN1/2-IN-1 is a cell-permeable compound that inhibits PKN1 and PKN2, with IC50 values of 16 nM and 210 nM, and Ki values of 8 nM and 108 nM, respectively. In NanoBRET assays, it shows intracellular PKN2 binding with an IC50 of 2.1 μM. This compound is applicable for investigating tumor cell migration and related physiological processes.

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