QS-21
Product Specifications
CAS Number
141256-04-4
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Molecular Formula
C92H148O46
Additionnal Information
QS-21 (QS-21-Api; Stimulon) is a natural saponin vaccine adjuvant derived from Quillaja saponaria bark that enhances both Th2 humoral and Th1 cell-mediated immune responses by acting on antigen-presenting cells (APCs) and T cells. It activates the NLRP3 inflammasome, leading to caspase-1-dependent release of IL-1β and IL-18 cytokines, which are critical for Th1 immunity and control of intracellular pathogens.
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