Zotizalkib
Product Specifications
CAS Number
2648641-36-3
Synonyms
TPX-0131
Target
ALK
Applications
Protein Tyrosine Kinase
Molecular Formula
C21H20F3N5O3
Additionnal Information
Zotizalkib (TPX-0131) is a compact macrocyclic potent CNS-penetrant, next-generation inhibitor of wild-type ALK and ALK-resistant mutations with an IC50 of 1.4 nM for wild-type ALK. It exhibits antitumor efficacy and can be used in non–small cell lung cancer research.
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