ML-7 HCl
Product Specifications
CAS Number
110448-33-4
Target
PKC
Applications
Cytoskeletal Signaling
Smiles
C1CNCCN (C1) S (=O) (=O) C2=CC=CC3=C2C=CC=C3I.Cl
Molecular Formula
C15H17IN2O2S.HCl
Additionnal Information
ML-7 is an inhibitor of smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 μM and displays reversible, ATP-competitive inhibition of Ca2+-calmodulin-dependent and -independent smooth muscle MLCKs. ML-7 also inhibits PKA and PKC with Ki of 21 μM and 42 μM, respectively.
Storage Conditions
2 years -80 in solvent
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