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Apoptozole

Product Specifications

CAS Number

1054543-47-3

Synonyms

Apoptosis Activator VII

Target

HSP (HSP90)

Applications

Cytoskeletal Signaling

Smiles

COC1=CC=C (C=C1) C2=C (N (C (=N2) C3=CC (=CC (=C3) C (F) (F) F) C (F) (F) F) CC4=CC=C (C=C4) C (=O) N) C5=CC=C (C=C5) OC

Molecular Formula

C33H25F6N3O3

Additionnal Information

Apoptozole (Apoptosis Activator VII) is an inhibitor of heat shock protein 70 (HSP70) and Hsc70 with dissociation constants Kd of 0.14 μM and 0.21 μM, respectively. It induces caspase-dependent apoptosis.

Storage Conditions

2 years -80 in solvent

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