Tyrphostin AG 1296
Product Specifications
CAS Number
146535-11-7
Synonyms
AG 1296
Target
C-Kit
Applications
Protein Tyrosine Kinase
Smiles
COC1=C (C=C2C (=C1) N=CC (=N2) C3=CC=CC=C3) OC
Molecular Formula
C16H14N2O2
Additionnal Information
Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR. Tyrphostin AG1296 inhibits FGFR and c-Kit with IC50 of 12.3 μM and 1.8 μM in Swiss 3T3 cells. Tyrphostin AG1296 induces dramatic apoptosis in A375R cells.
Storage Conditions
2 years -80 in solvent
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